Fig. 8: Propofol promotes cytoprotective mechanisms via miR-20b. | Cell Death & Disease

Fig. 8: Propofol promotes cytoprotective mechanisms via miR-20b.

From: Propofol-induced MiR-20b expression initiates endogenous cellular signal changes mitigating hypoxia/re-oxygenation-induced endothelial autophagy in vitro

Fig. 8

miR-20b expression induced by propofol promotes endogenous cytoprotective mechanisms of the METTL3/miR-20b/ULK1 regulatory “network” in hypoxia/re-oxygenation injury. METTL3: methyltransferase-like 3; DGCR8: DiGeorge critical region 8; ULK1: Unc-51-like kinase 1; mRNA: Messenger RNA; pri- miR-20b: primary microRNA-20b; pre-miR-20b: precursor microRNA-20b; miR-20b: microRNA-20b.

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