Fig. 4: Knockdown of SNAI3-AS1 represses tumor growth and metastasis in vivo. | Cell Death & Disease

Fig. 4: Knockdown of SNAI3-AS1 represses tumor growth and metastasis in vivo.

From: LncRNA SNAI3-AS1 promotes PEG10-mediated proliferation and metastasis via decoying of miR-27a-3p and miR-34a-5p in hepatocellular carcinoma

Fig. 4

a Representative images of nude mice models and formed tumors that were subcutaneously injected with SNAI3-S1-shRNA and NC cells. b, c Effect of SNAI3-S1 knockdown on HCC growth in vivo according to the tumor weight and tumor growth curve. *P < 0.05, **P < 0.01. d, g, h H&E and immunofluorescence staining using antibodies against Ki-67and PEG10 was used to assess proliferation capacity.**P < 0.01. Scale bars: 20 μm. e, f Representative images of pulmonary metastatic models and H&E staining of metastatic nodules in the lungs (×200 and ×400), **P < 0.01. Scale bars: 20 and 10 μm.

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