Fig. 5: ALV-J inhibits autophagy through the GADD45β/MEKK4/p38MAPK signaling pathway.

a, b DF-1 cells or CEF cells were treated with SB203580 and SP600125, inhibitors of the p38MAPK and JNK signaling pathways, respectively, and infected with ALV-J for 24 h. Expression levels of gp37, LC3B, SQSTM1, Atg5, p-p38, p38, p-JNK, and JNK were analyzed using western blotting.