Fig. 6: silenced HMBOX1 attenuated shWTAP-repressed osteosarcoma growth and metastasis in vivo. | Cell Death & Disease

Fig. 6: silenced HMBOX1 attenuated shWTAP-repressed osteosarcoma growth and metastasis in vivo.

From: WTAP promotes osteosarcoma tumorigenesis by repressing HMBOX1 expression in an m6A-dependent manner

Fig. 6

a The expression levels of HMBOX1 in osteosarcoma mice models. b Knockdown of HMBOX1 effectively alleviated shWTAP-repressed osteosarcoma growth in mice. c The orthotopic xenograft tumor and d lung metastasis were detected using a vivo bioluminescence imaging system. Representative images and a histogram are shown (n = 8 each group).

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