Fig. 1: CRNDE was overexpressed in HCC and was correlated with clinical parameters. | Cell Death & Disease

Fig. 1: CRNDE was overexpressed in HCC and was correlated with clinical parameters.

From: LncRNA CRNDE facilitates epigenetic suppression of CELF2 and LATS2 to promote proliferation, migration and chemoresistance in hepatocellular carcinoma

Fig. 1

a Relative expression of CRNDE in HCC tumor tissues and adjacent tissues was determined by qPCR, n = 47. b Expression levels of CRNDE at different TNM stages were determined by qPCR. c Expression levels of CRNDE in tissue with lymph node metastasis or not were determined by qPCR. d A web server for analyzing the RNA sequencing expression data named GEPIA was accessed, and CRNDE expression in healthy human bodies and in cancer patients was compared in LIHC database. e GEPIA showed expression of CRNDE at TNM stages I, II, III, and IV in LIHC database. f, g Correlation between CRNDE expression and overall survival (f), or disease-free survival (g) were determined in GEPIA. (h) In vitro relative expression of CRNDE was compared in HCC cell lines HCCC-9810, the Bel-100, Bel-7402, Bel-7405, Huh-7, SMMC-7721, WRL68, HepG2, and the immortalized human hepatic cell line THLE3. *P < 0.05, **P < 0.01, and ***P < 0.001.

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