Fig. 1: CircMBOAT2 was upregulated in CRC tissues.

a Differential expression of circRNA in CRC tissues and matched normal tissues (CRC: tumor tissues, n = 1; CRC_NT: adjacent normal tissues, n = 1; CRC_rep: normal mucosa tissues, n = 2). b Five most upregulated circRNAs in CRC tissues analyzed by RNA deep sequencing technology and bioinformatics. c Five most downregulated circRNAs in CRC tissues analyzed by RNA deep sequencing technology and bioinformatics. d Genomic loci of the MBOAT2 gene and circMBOAT2. The expression of circMBOAT2 was detected by qRT-PCR and validated by Sanger sequencing. e Expression of circMBOAT2 in colorectal cancer tissues and adjacent normal tissues (n = 169, the 2−ΔΔCt method).