Fig. 4: Knockdown of circMBOAT2 could inhibit the invasion and migration of CRC cells in vitro. | Cell Death & Disease

Fig. 4: Knockdown of circMBOAT2 could inhibit the invasion and migration of CRC cells in vitro.

From: Circular noncoding RNA circMBOAT2 is a novel tumor marker and regulates proliferation/migration by sponging miR-519d-3p in colorectal cancer

Fig. 4

a After circMBOAT2 knockdown, the invasive capability of HCT-8 and SW480 cells decreased significantly. b Interference with the expression of circMBOAT2 significantly inhibited the migratory capability of HCT-8 and SW480 cells. c, d Cell migratory (c) and invasive (d) capabilities were promoted in HCT-116 cells after transfection with pcDNA3.1-circMBOAT2. e, f Flow cytometry results showed that circMBOAT2 knockdown promoted apoptosis in HCT-8 cells (c) but not in SW480 cells (d). **P < 0.01, ***P < 0.005, ****P < 0.001.

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