Table 1 Correlation between the expression of circMBOAT2 and clinical pathological factors in CRC tissues.
Variables | No. of patients | circMBOAT2 (high) | circMBOAT2 (low) | χ2 | P |
|---|---|---|---|---|---|
Gender | Â | Â | Â | 1.33 | 0.250 |
Male | 116 | 57 (73.08) | 59 (64.84) | Â | Â |
Female | 53 | 21 (26.92) | 32 (35.16) | Â | Â |
Age (year) | Â | Â | Â | 1.43 | 0.232 |
≤60 | 95 | 40 (51.28) | 55 (60.44) |  |  |
>60 | 74 | 38 (48.72) | 36 (39.56) | Â | Â |
Tumor location | Â | Â | Â | 0 | 0.981 |
Colon | 67 | 31 (39.74) | 36 (39.56) | Â | Â |
Rectum | 102 | 47 (60.26) | 55 (60.44) | Â | Â |
Tumor diameter (cm) | Â | Â | Â | 1.45 | 0.228 |
≤5 | 57 | 30 (38.46) | 27 (29.67) |  |  |
>5 | 112 | 48 (61.54) | 64 (70.33) | Â | Â |
Tumor differentiation | Â | Â | Â | 1.62 | 0.203 |
Poor | 34 | 19 (24.36) | 15 (16.48) | Â | Â |
Well/moderate | 135 | 59 (75.64) | 76 (83.52) | Â | Â |
pT stage | Â | Â | Â | 0.01 | 0.936 |
T1–3 | 123 | 57 (73.08) | 66 (72.53) |  |  |
T4 | 46 | 21 (26.92) | 25 (27.47) | Â | Â |
pN stage | Â | Â | Â | 0.36 | 0.551 |
N0 | 93 | 41 (52.56) | 52 (57.14) | Â | Â |
N1–2 | 76 | 37 (47.44) | 39 (42.86) |  |  |
Distant metastasis (M stage) | Â | Â | Â | 6.45 | 0.011 |
M0 | 155 | 67 (85.9) | 88 (96.7) | Â | Â |
M1 | 14 | 11 (14.1) | 3 (3.3) | Â | Â |
pTNM stage | Â | Â | Â | 13.27 | <0.001 |
I–II | 73 | 22 (28.21) | 51 (56.04) |  |  |
III–IV | 96 | 56 (71.79) | 40 (43.96) |  |  |
Perineural invasion | Â | Â | Â | 0.01 | 0.910 |
Yes | 19 | 9 (11.54) | 10 (10.99) | Â | Â |
No | 150 | 69 (88.46) | 81 (89.01) | Â | Â |
Lymphovascular invasion | Â | Â | Â | 9.8 | 0.002 |
Yes | 8 | 8 (10.26) | 0 (0) | Â | Â |
No | 161 | 70 (89.74) | 91 (100) | Â | Â |
Postoperative recurrence or metastasis | Â | Â | Â | 0.01 | 0.906 |
Yes | 34 | 16 (20.51) | 18 (19.78) | Â | Â |
No | 135 | 62 (79.49) | 73 (80.22) | Â | Â |
