Fig. 1: Proferroptotic gene ACSL4 TEC ferroptosis-related genes were increased in human kidney diseases. | Cell Death & Disease

Fig. 1: Proferroptotic gene ACSL4 TEC ferroptosis-related genes were increased in human kidney diseases.

From: XJB-5-131 inhibited ferroptosis in tubular epithelial cells after ischemia−reperfusion injury

Fig. 1

a Transmission electron microscopy of human tubular epithelial cells with kidney diseases, including IgA nephropathy (IgAN), membranous glomerulonephritis (MN), and acute tubular injury (ATI). The white arrowheads indicated shrunken mitochondria with outer membrane rupture. Scale bars = 500 nm. b The representative image and graph of ACSL4 immunostaining in TECs in human kidney diseases. c Correlations between the integrated option density (IOD) of intrarenal ACSL4 + immunostaining and SCr, BUN, eGFR in ATI patients. AOI area of interesting. Original magnification ×400. Scale bars = 50 μm. Data were presented as the means ± SEM. *p < 0.05, **p < 0.01.

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