Table 1 ATI patients in the ACSL4high group showed a decline of kidney function.

From: XJB-5-131 inhibited ferroptosis in tubular epithelial cells after ischemia−reperfusion injury

Variables

All (n = 45)

ACSL4low (n = 30)

ACSL4high (n = 15)

P

Gender

    

 Male

25

15 (50%)

10 (66.7%)

 

 Female

20

15 (50%)

5 (33.3%)

0.2888

Age (years)

46.0 (27.5, 54.5)

50.0 (34.0, 57.25)

33.0 (26.0, 52.0)

0.0495

Hematuria

    

 <3+ (%)

21

19 (70.4%)

12 (84.6%)

 

 ≥3+ (%)

14

11 (29.6%)

3 (15.4%)

0.2549

Proteinuria

    

 <3+ (%)

25

18 (60.0%)

7 (46.7%)

 

 ≥3+ (%)

20

12 (40.0%)

8 (53.3%)

0.3961

 Hb(g/L)

122.0 (107.0,135.0)

123.0 (114.8,136.8)

114.5 (98.93,130.1)

0.2533

Blood urea nitrogen (mmol/L)

7.4 (6.1, 12.8)

7.2 (5.7, 8.1)

13.8 (7.4, 16.3)

0.0151

Serum creatinine (μmol/L)

128.0 (100.5, 237.5)

121.5 (94.8, 136.0)

244.0 (127.0, 340.0)

0.0026

Serum uric acid (μmol/L)

383.1 (324.8, 423.5)

377.2 (324.0, 416.2)

415 (337.0, 417.0)

0.1980

eGFR (mL/min/1.73 m2)

51.5 (25.9, 58.8)

56.2 (40.6, 69.4)

26.7 (18.9, 55.0)

0.0084

Serum albumin (g/L)

37.2 (25.7, 42.7)

37.7 (30.2, 44.7)

34.4 (18.1, 40.8)

0.1288

Serum total cholesterol

4.7 (4.0, 7.5)

4.6 (3.8, 5.9)

5.0 (4.0, 9.1)

0.2485

  1. Data are presented as a percentage or median (25th−75th percentiles); eGFR (ml/min/1.73 m2) = 186 × Scr − 1.154 × age − 0.203 × 0.742 (if female) × 1.227; comparisons between groups were performed by chi-squared tests.
  2. Hb hemoglobin, eGFR estimated glomerular filtration rate.
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