Fig. 6: The role of Skp2 in 20(S)-Rh2E2-induced anti-cancer effect. | Cell Death & Disease

Fig. 6: The role of Skp2 in 20(S)-Rh2E2-induced anti-cancer effect.

From: Novel ginsenoside derivative 20(S)-Rh2E2 suppresses tumor growth and metastasis in vivo and in vitro via intervention of cancer cell energy metabolism

Fig. 6

a Effect of 20(S)-Rh2E2 and 20(R)-Rh2E2 on the expression of Cdk inhibitors during cell cycle progression of LLC-1 cells. b Effect of 20(S)-Rh2E2 and 20(R)-Rh2E2 on Skp2 signaling pathway in LLC-1 cells. LLC-1 cells were treated with 20(S)/(R)-Rh2E2 (40 µM, 60 µM, 80 µM) for 24 h, respectively. Representative immunoblots and the protein quantification are shown; mean ± S.D., n = 3; *P < 0.05, **P < 0.01, ***P < 0.001, one-way ANOVA analysis.

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