Fig. 3: Effects of ELA on DOCA/salt-induced renal fibrosis. | Cell Death & Disease

Fig. 3: Effects of ELA on DOCA/salt-induced renal fibrosis.

From: ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway

Fig. 3

a Representative Picro-sirius red staining of collagen in renal cortex and medulla. Scale bar, 100 µm. b Summarized Picro-sirius red staining in renal cortex and medulla. c Representative immunohistochemical staining of α-SMA in renal cortex and medulla. Scale bar, 50 µm. d Summarized immunohistochemical staining in renal cortex and medulla. e Representative immunoblots of Collagen-1 and α-SMA in renal cortex and medulla as well as summarized intensities of blots. N = 6 per group. *P < 0.05 versus Ctrl group; #P < 0.05 versus DOCA/salt group. α-SMA α-smooth muscle actin.

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