Fig. 5: Effects of ELA on DOCA/salt-induced NADPH oxidase formation and activation. | Cell Death & Disease

Fig. 5: Effects of ELA on DOCA/salt-induced NADPH oxidase formation and activation.

From: ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway

Fig. 5

a mRNA levels of p22phox, gp91phox, p47phox, and p67phox subunits of NADPH oxidase in the renal cortex. b mRNA levels of p22phox, gp91phox, p47phox, and p67phox subunits of NADPH oxidase in the renal medulla. c Representative immunoblots of p22phox and p47phox and summarized intensities of blots. d Intracellular NADP+/NADPH in renal cortex and medulla. N = 6 per group. *P < 0.05 versus Ctrl group; #P < 0.05 versus DOCA/salt group.

Back to article page