Fig. 1: PIK3R3 is overexpressed and p21 is underexpressed in colorectal cancer.
From: PIK3R3 inhibits cell senescence through p53/p21 signaling
a Expression analysis of PIK3R3 in CRC tissues and normal intestinal tissues from a dataset (GSE21510) of GEO database. b Gene ontology (GO) analysis of PIK3R3 co-expression genes. c Correlation analysis of PIK3R3 and p21 in CRC tissues from the dataset (GSE21510). d IHC staining of typical samples from CRC and adjacent tissues. e Quantification of PIK3R3 and p21 expression in tumor groups and normal epithelial groups. f The protein levels of PIK3R3 and p21 in CRC and adjacent normal tissues. These numeral results were displayed as mean ± SD, *p < 0.05, **p < 0.01, ***p < 0.001, t-test.
