Fig. 6: Overexpressed PIK3R3 promotes cell proliferation and inhibits cellular senescence in vivo. | Cell Death & Disease

Fig. 6: Overexpressed PIK3R3 promotes cell proliferation and inhibits cellular senescence in vivo.

From: PIK3R3 inhibits cell senescence through p53/p21 signaling

Fig. 6

a Tumor volume of three groups were measured over time. b Tumor gross observation of three groups (vector, PIK3R3, and PIK3R3 + p53). c Tumor weight of three groups (vector, PIK3R3, and PIK3R3 + p53). d IHC assays of PIK3R3, p53, p21, Ki-67, and β-Gal from three groups. e Quantification of p21 expression from three groups. f Quantification of the proportion of β-Gal-positive cells from three groups. g WB of PIK3R3, p53, and p21 in three different groups. These numeral results were displayed as mean ± SD, *p < 0.05, **p < 0.01, ***p < 0.001, t-test.

Back to article page