Fig. 5: E/M@FA-LPs led to ferroptosis. | Cell Death & Disease

Fig. 5: E/M@FA-LPs led to ferroptosis.

From: MT1DP loaded by folate-modified liposomes sensitizes erastin-induced ferroptosis via regulating miR-365a-3p/NRF2 axis in non-small cell lung cancer cells

Fig. 5

a E/M@FA-LPs contributed to ferroptosis in A549 cell as confirmed by flow cytometry. b The A549 and H1299 cells treated with E/M@FA-LPs showed shrunken mitochondria with increased membrane density. Scale bar represents 5 μm. c E/M@FA-LPs increased intracellular ferrous iron in A549 and H1299 cells. All experiments were repeated at least three times and representative data are shown. Data are means ± SEM; **p < 0.01.

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