Fig. 3: Sp promotes recovery of dopaminergic neurons in park flies.

a Confocal images of Drosophila brains showing architecture of dopaminergic neurons labeled with GFP under wild type and mutant backgrounds, left untreated or treated with Sp. Scale bar: 50 µm. b The fluorescence intensity (FI) profile of park¹³ or wild-type Drosophila dopaminergic neurons expressing mt-roGFP under 2.5 mM Sp treated or untreated conditions. Data is represented as fold difference over untreated wild-type control. Bars denote mean ± s.e.m.; n = 3, **P (t-test) <0.001. c Kaplan Meier curve representing survivability pattern for wild type and park¹³ (p¹³) flies untreated or treated continuously with 2.5 mM Sp; ***P (Mantel-Cox test) <0.0001. UT – untreated with Sp.