Fig. 4: LINC00319/miR-199a-5p/FZD4 axis contributed to the malignance of OSCC in vivo. | Cell Death & Disease

Fig. 4: LINC00319/miR-199a-5p/FZD4 axis contributed to the malignance of OSCC in vivo.

From: CCL18-induced LINC00319 promotes proliferation and metastasis in oral squamous cell carcinoma via the miR-199a-5p/FZD4 axis

Fig. 4

a The image and weight of control samples and xenograft tumor tissues formed by shLINC00319-transfected HSC6 cells (n = 5). b The volume of xenograft tumors at the time of every 7 days (n = 5). c The histomorphology of xenograft tumors with LINC00319 silencing and control was analyzed by HE staining. d–f The mRNA expression level of LINC00319 (d), miR-199a-5p (e), and FZD4 (f) in LINC00319-silenced xenograft tumors and control (n = 5). g, h The protein level of FZD4 in LINC00319-silenced xenograft tumors and control was analyzed by western blotting (g) and IHC (h) (n = 5). i The protein of EMT markers and angiogenesis markers were evaluated by IHC. *P < 0.05; **P < 0.01; ***P < 0.001.

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