Table 2 Correlation of clinic-pathological features with SPATS2 expression in ZZU HCC cohort.

From: SPATS2, negatively regulated by miR-145-5p, promotes hepatocellular carcinoma progression through regulating cell cycle

 

Univariate analysis

Multivariate analysis

HR

95% CI

P-value

HR

95% CI

P-value

Age (>53 vs. ≤53)

1.143

0.884–1.413

0.863

   

Gender (Female vs. ≤ Male)

0.846

0.534–1.342

0.479

   

Pathogenesis (Virus vs. ≤Others)

0.784

0.341–1.341

0.243

   

AFP (>20 vs. ≤20)

1.270

0.684–1.654

0.347

   

Cirrhosis (Present vs. Absent)

1.515

0.812–2.825

0.192

   

Vascular invasion (Present vs. Absent)

1.848

1.225–2.793

0.003

2.126

1.884–2.985

0.019

TNM stage (III & IV vs. I & II)

3.333

2.262–4.902

0.000

3.954

3.047–5.178

0.000

Tumor size (>5 vs. ≤5)

1.751

1.198–2.564

0.004

1.499

0.926–1.887

0.274

Tumor multiplicity (Multiple vs. Single)

2.964

2.176–3.47

0.019

1.984

1.698–2.659

0.041

SPATS2 expression (High vs. Low)

3.265

2.560–4.165

0.005

2.731

2.014–3.654

0.029

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