Fig. 1: METTL3 regulates the m6A level in CC tissue and cells. | Cell Death & Disease

Fig. 1: METTL3 regulates the m6A level in CC tissue and cells.

From: N6-methyladenosine METTL3 promotes cervical cancer tumorigenesis and Warburg effect through YTHDF1/HK2 modification

Fig. 1

a M6A quantitative analysis showed the percentage of m6A content in the CC tissue and adjacent normal tissue. b M6A quantitative analysis showed the percentage of m6A content in CC cells (SiHa, CaSki) and normal cells (HaCaT). c M6A quantitative analysis showed the percentage of m6A content in CC cells (SiHa, CaSki) transfected with METTL3 knockdown. d MeRIP-Seq analysis revealed the m6A peaks distributed at 3’-UTR, 5’-UTR and coding sequence (CDS). e Proportion analysis illustrated the m6A peaks were distributed in the 3’-UTR, CDS, 5’-UTR and stop codon. f Volcano plot of MeRIP-Seq showed the dysregulated m6A peaks in the CC cells. Data are displayed as mean ± standard deviation. **p < 0.01 vs. control.

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