Fig. 4: METTL3 promotes the proliferation and invasion of CC cells. | Cell Death & Disease

Fig. 4: METTL3 promotes the proliferation and invasion of CC cells.

From: N6-methyladenosine METTL3 promotes cervical cancer tumorigenesis and Warburg effect through YTHDF1/HK2 modification

Fig. 4

a Colony formation assay indicated the clones’ number of CC cells. SiHa cells were transfected with METTL3 knockdown, and CaSki cells were transfected with METTL3 overexpression. b CCK-8 assay illustrated the proliferative ability with METTL3 knockdown or METTL3 overexpression. c Flow cytometry for apoptosis indicated the apoptotic rate with METTL3 knockdown and METTL3 overexpression. d Flow cytometry for cell-cycle analysis demonstrated the cellular distribution at G0/G1, S, G2/M phase. Data are displayed as mean ± standard deviation. **p < 0.01 vs. control. *p < 0.05 vs. control.

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