Table 1 Table characteristics of the study cohort.

From: RNF180 mediates STAT3 activity by regulating the expression of RhoC via the proteasomal pathway in gastric cancer cells

Characteristics

Case

5-YSR (%)

P-value†

Hazard ratio (95 % CI)

P-value‡

Gender

  

0.269

  

Male

78

36.60

   

Female

35

31.97

   

Age at surgery (years)

  

0.178

  

<65

71

37.68

   

≥65

42

30.93

   

Tumor location

  

0.015

1.275 (1.014–1.603)

0.038

Upper third

17

39.06

   

Middle third

15

40.73

   

Lower third

51

38.10

   

>2/3 stomach

30

26.217

   

Lauren classification

  

0.683

  

Intestinal

29

33.83

   

Diffuse

84

35.63

   

Tumour size (cm)

  

0.055

  

<4

19

50.21

   

≥4

94

32.13

   

Type of gastrectomy

  

0.299

  

Total

42

30.60

   

Proximal subtotal

14

36.21

   

Distal subtotal

57

38.28

   

Soft tissue invasion

  

0.093

  

No

77

32.14

   

Yes

36

41.64

   

pT stage

  

0.964

  

pT2

7

34.29

   

pT3

9

35.78

   

pT4a

90

34.99

   

pT4b

7

37.57

   

pN stage

  

0.005

1.258 (1.092–1.450)

0.002

pN0

23

51.52

   

pN1

14

37.93

   

pN2

25

32.40

   

pN3a

26

28.12

   

pN3b

25

28.68

   

RNF180 expression*

  

0.006

0.628 (0.405–0.974)

0.038

Low

43

29.72

   

High

70

38.51

   
  1. Values in parentheses are 95 percent confidence intervals.
  2. *Determined by immunohistochemical staining.
  3. †Log-rank test.
  4. ‡Cox proportional hazards model.
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