Fig. 3: ZJQ-24 induces cell cycle arrest and apoptosis in HCC cells. | Cell Death & Disease

Fig. 3: ZJQ-24 induces cell cycle arrest and apoptosis in HCC cells.

From: Indole hydrazide compound ZJQ-24 inhibits angiogenesis and induces apoptosis cell death through abrogation of AKT/mTOR pathway in hepatocellular carcinoma

Fig. 3

A Representative DNA histograms and quantitative analysis of cell cycle in HepG2 and HUH-7 cells after ZJQ24 treatment. B Induction of apoptosis and quantitative assessment of early apoptotic cells by ZJQ-24 treatment in HepG2 and HUH-7 cells. C The cellular morphology of HepG2 and HUH-7 cells after ZJQ-24 treatment. D Detection of apoptosis proteins following ZJQ-24 treatment for 24 h, lysates from HepG2 samples were subjected to SDS-PAGE and probed with antibody to PARP and caspase-3. **P < 0.01, ***P < 0.001 vs. control group.

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