Fig. 3: CyTOF revealed that administration of sPD-L1 reduced monocyte-derived macrophages.
From: Soluble PD-L1 improved direct ARDS by reducing monocyte-derived macrophages
A The frequency of common immune cells in CD45+live cells by manual gating. B Gate strategy for monocyte-derived macrophages in one of the samples. C The frequency of significant reduced cluster in CD45+live cells (cluster 44). D The viSNE plot layered with the significant reduced cluster analyzed by X shift (n = 4/each group) (cluster 44). E The viSNE plots of expression of the markers that were highly expressed in the significantly changed clusters (cluster 44). The color gradient (from low (blue) to high (red)) indicates the intensity of the markers. F The viSNE plots of the markers of M1 like and M2 like macrophages in cluster 44. P value was analyzed by Man–Whitney test.
