Fig. 5: The protective role of sPD-L1 was diminished in ARDS mice with monocytes/macrophages depletion.
From: Soluble PD-L1 improved direct ARDS by reducing monocyte-derived macrophages
A The flow cytometry of monocytes and macrophages in blood, lung and BALF of CL or L injected mice (n = 5/group). B The statistical graph of the frequency in CD45+cells of the cells in graph A (n = 5/group). C The protein concentration in BALF of mice with different treated methods (n = 5/group). D The cell counts in BALF of mice with different treated methods (n = 5–6/group). E) The wet to dry ratio of lung tissue of mice with different treated methods (n = 5–6/group). F The HE staining of lung tissue from different treated mice (n = 5–6/group). Each value represents the mean ± SEM of three independent experiments. The experiments have been repeated for at least three times. *P < 0.05, **P < 0.01, ***P < 0.001, analyzed by t test. Mo/Ma, monocyte/macrophage, MDM monocyte-derived macrophages, Neu, neutrophil.
