Fig. 3: Overexpression of LINC00472 alters the surface morphology and mechanical properties of cells. | Cell Death & Disease

Fig. 3: Overexpression of LINC00472 alters the surface morphology and mechanical properties of cells.

From: LncRNA LINC00472 regulates cell stiffness and inhibits the migration and invasion of lung adenocarcinoma by binding to YBX1

Fig. 3

a Representative AFM deflection images of A549 and PC-9 cells transfected with the LINC00472 overexpression vector. b 3D distribution of the cell heights of A549 and PC-9 cells transfected with the LINC00472 overexpression vector. c LINC00472 affects the surface morphology (Rq) of A549 and PC-9 cells. d Analysis of the adhesion force of the A549 and PC-9 cells. e Analysis of the stiffness of A549 and PC-9 cells. f Analysis of the Young’s modulus of A549 and PC-9 cells. g Representative AFM deflection images of BEAS-2B, 3D distribution of the cell heights of BEAS-2B, and analysis of surface morphology (Rq) of BEAS-2B cells. The force curve was used to calculate the mechanical properties. Data on adhesion, stiffness, Rq and Young’s modulus are based on analyses of the JPK image processing software. Vector: the empty vector; LINC00472: the LINC00472 overexpression vector. *p < 0.05; **p < 0.01.

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