Fig. 6: TNFα increased in bevacizumab resistance tumors. | Cell Death & Disease

Fig. 6: TNFα increased in bevacizumab resistance tumors.

From: Tumor necrosis factor α inhibition overcomes immunosuppressive M2b macrophage-induced bevacizumab resistance in triple-negative breast cancer

Fig. 6

a Serum concentration-time curve of TNFα in MDA-MB-231R bearing mice treated with bevacizumab or saline was detected by ELISA. n = 3/group. *P < 0.05; **P < 0.01 by t test. Error bars represent s.d. b TNFα expression levels in breast cancer patients treated with bevacizumab at different clinical stages. Error bars represent s.d. c VEGF expression levels in breast cancer patients treated with bevacizumab at different clinical stages. Error bars represent s.d. d CCL1 expression levels in breast cancer patients treated with bevacizumab at different clinical stages. Error bars represent s.d. *P < 0.05 by t test.

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