Fig. 1: Human miR-205 host gene (MIR205HG) transcription unit.

The schematic representation shows the transcription factor responsive elements (REs) and methylation sites (CpG islands) localized upstream of MIR205HG and of pre-miR-205 sequence. The miR-205 and MIR205HG regulatory regions are depicted in orange (region 1) and in aquamarine (region 2).