Table 2 Summary of the reported functions and mechanisms of action of MIR205HG lncRNA in different tissue/tumor types.
Species | Tissue/cancer type | Biological role | Mechanism of action | References |
|---|---|---|---|---|
Human | LUSC | Cell proliferation, migration, EMT | ceRNA for miR-299–3p | |
Human | LUSC | Cell proliferation, migration, apoptosis | Bcl-2 and Bax regulation | |
Human | Cervical cancer | Cell proliferation, migration, apoptosis | SRSF1/KRT17 axis regulation | |
Human | Cervical cancer | Cell proliferation, migration, apoptosis | ceRNA for miR-122-5p | |
Human | HNSCC | Cell proliferation, migration | ceRNA for miR-590-3p | |
Human | Prostate basal cells | Basal-luminal differentiation | transcriptional repression of interferon genes | |
Mouse | Pituitary | Growth hormone and prolactin production | Pit1 regulation |
