Fig. 7: Schematic deacetylation of PKM2 at K62 in HCC.

HDAC8 plays a crucial role in deacetylation of PKM2 at K62. Then the metabolic activity and nuclear relocation of PKM2 was narrowed down and increased separately.

HDAC8 plays a crucial role in deacetylation of PKM2 at K62. Then the metabolic activity and nuclear relocation of PKM2 was narrowed down and increased separately.