Fig. 5: Chemoresistant MB is susceptible to combination treatment of vincristine with cisplatin or niclosamide. | Cell Death & Disease

Fig. 5: Chemoresistant MB is susceptible to combination treatment of vincristine with cisplatin or niclosamide.

From: Autocrine IL-6/STAT3 signaling aids development of acquired drug resistance in Group 3 medulloblastoma

Fig. 5

Med8A-S, Med8A-R, and Med8A-S-IL6+ cells were treated with vincristine alone or in combination with (a) cisplatin and (b) niclosamide at the indicated concentrations for 48 h and cell viability assessed with CTB. As plotted is the mean ± SD of three replicates; ***p < 0.001, two-way ANOVA with Tukey’s multiple comparison test (Significance not highlighted in the figure is presented in Supplementary Table 1).

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