Fig. 1: IDO1 expression level was enhanced in fibrotic livers induced by BDL. | Cell Death & Disease

Fig. 1: IDO1 expression level was enhanced in fibrotic livers induced by BDL.

From: Indoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis

Fig. 1

A Serum concentrations of AST and ALT were measured from sham, BDL-operated mice (n ≥ 3). B H&E staining of liver sections. C Liver samples were processed for immunofluorescence co-staining for IDO1 with α-SMA. Slides were counterstained with DAPI. D Western blot analysis of the expression of IDO1 and α-SMA in the livers of WT control and model mice (n = 3). E GAPDH served as a loading control. The density of GAPDH, α-SMA and IDO1 protein in D were measured using image J software and quantified in a bar graph, respectively. In all panels, scale bars, 100 mm. The data are presented as the means ± SEM. P < 0.05 is considered statistically significant. Statistical analysis was analyzed by independent-samples t-test.

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