Fig. 1: The DEP identification and correlation analysis with HCC clinicopathological traits.

A OPLS-DA analysis of protein expression in hepatocellular carcinoma (CA) and paired adjacent normal (NO) samples. B Volcano plot showing significantly differentially expressed proteins. UP upregulated proteins were labeled in purple, DW downregulated proteins were labeled in green, NoDiff proteins with no significant differential expression. C Hierarchical clustering of differentially expressed proteins in hepatocellular carcinoma (CA) and paired adjacent normal (NO) samples. Clinical traits, including PT, DBIL, TBIL, AST, ALT, tumor number, embolus, differentiation, capsule, AFP, cirrhosis, gender, and age, were shown.