Table 1 Characteristics of patients/healthy volunteers.

From: The HIV protease inhibitor Saquinavir attenuates sepsis-induced acute lung injury and promotes M2 macrophage polarization via targeting matrix metalloproteinase-9

Characteristics

Non-sepsis (n = 10)

Sepsis (n = 14)

Age, years

58.50 ± 2.75

59.93 ± 1.95

Male, n (%)

7 (70)

10 (71.43)

MMP-9 (ng/ml)

119.0 ± 10.71

457.6 ± 70.40

APACHE III score

–

36.14 ± 4.20

SOFA score

–

6.71 ± 0.53

Etiology, n (%)

 Pneumonia

–

6 (42.86)

 Peritonitis

–

3 (21.43)

 Multiple injuries

–

2 (14.28)

 Urosepsis

–

2 (14.28)

 Other

–

1 (7.14)

Comorbidities, n

 None

9

3

 Respiratory

0

6

 Cardiovascular

0

9

 Diabetes

1

6

 Chronic renal disease

0

2

Ventilatory support, n (%)

–

3 (21.43)

30-day mortality, n (%)

0 (0)

2 (14.28)

  1. Data are expressed as the mean ± SEM or number (%).
  2. APACHE III Acute Physiology, Age, Chronic Health Evaluation III, SOFA Sequential Organ Failure Assessment.
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