Fig. 1: The expression of hsa_circ_0007456 is downregulated in HCC and is negatively correlated with the patients’ prognosis.

A The schematic structure of hsa_circ_0007456. B The relative expression levels of hsa_circ_0007456 in the indicated cell lines. C The relative expression levels of hsa_circ_0007456 in tumor tissues and the adjacent normal tissues of the HCC patients (n = 72). D The relative expression levels of hsa_circ_0007456 in the primary tumor tissues (n = 28) and the portal vein tumor thrombus (n = 28). E The relative expression levels of hsa_circ_0007456 in the tumor tissues of T1-2 patients (n = 51) and T3-4 patients (n = 21). F The relative expression levels of hsa_circ_0007456 in the tumor tissues of N0 patients (n = 53) and N1 patients (n = 19). G The relative expression levels of hsa_circ_0007456 in the tumor tissues of stage I–II patients (n = 47) and stage III-IV patients (n = 25). Data are presented as mean ± SD. *p < 0.05; **p < 0.01.