Fig. 3: GSK-J4 inhibits cellular function and in vivo experiments. | Cell Death & Disease

Fig. 3: GSK-J4 inhibits cellular function and in vivo experiments.

From: KDM6B is an androgen regulated gene and plays oncogenic roles by demethylating H3K27me3 at cyclin D1 promoter in prostate cancer

Fig. 3

A The IC50 values of GSK-J4 for viability inhibition in PC3 and C42B cells are shown. Error bars means SD, n = 3 independent repeats. B The colony formation abilities of PC3 and C42B cells treated with GSK-J4 are shown. C A cell cycle analysis of PC3 and C42B cells treated with GSK-J4 was performed. D An apoptosis analysis of PC3 and C42B cells treated with GSK-J4 was performed. E The growth curve of subcutaneous xenograft of C42B cells treated with GSK-J4. Error bars mean SD, six mice in each group (*p < 0.05).

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