Fig. 3: miR-567 promoted chemosensitivity of trastuzumab treatment in vivo. | Cell Death & Disease

Fig. 3: miR-567 promoted chemosensitivity of trastuzumab treatment in vivo.

From: RETRACTED ARTICLE: Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer

Fig. 3

a A schematic outline of the experimental design. b Effect of miR-567 silence on transplanted tumor growth from SKBR-3 cells. Representative images of tumors as indicated in left panel and tumor growth as indicated in right panel, *P < 0.05. c Effect of miR-567 overexpression on transplanted tumor growth from SKBR-3-TR cells. Representative images of tumors as indicated in the left panel and tumor growth as indicated in the right panel, *P < 0.05. d Representative images of tumor samples derived from SKBR-3 cells that were stained with Ki67 by immunohistochemistry (IHC, left panel) and quantified (right panel); scale bars: 50 μm, **P < 0.01 compared with control inhibitor. e Representative images of tumor samples derived from SKBR-3-TR cells that were stained with Ki67 by IHC (left panel) and quantified (right panel); scale bars: 50 μm, **P < 0.01 compared with control mimics.

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