Fig. 1: Correlation analysis between B7-H3 and CD31 in tissue samples from CRC patients.

a Representative images of immunohistochemistry (IHC) for B7-H3 and CD31 in CRC tissues and matched normal tissues from the 125 clinical CRC patients. Scale bar, 100 μm. b, c B7-H3 (b) and CD31 (c) protein expression based on their staining index in CRC specimens and matched normal tissues. d CD31 protein expression is shown in patients stratified into B7-H3 low (<median value) and B7-H3 high (>median value) groups. e Correlation analysis of the staining index of the protein expression levels of B7-H3 and CD31 in human CRC specimens (n = 125). The correlation coefficient (r) is shown. The data represent the means ± SEM. ***P < 0.001.