Fig. 6: TUG1 promotes tumor metastasis in vivo. | Cell Death & Disease

Fig. 6: TUG1 promotes tumor metastasis in vivo.

From: The long noncoding RNA TUG1 is required for TGF-β/TWIST1/EMT-mediated metastasis in colorectal cancer cells

Fig. 6

a QRT-PCR was used to confirm the effects of TUG1 knockdown after transfection of TUG1 shRNA in LoVo cells, compared with the LV-NC group: ***P < 0.001. b Representative images of luciferase expression from lung metastasis of the normal saline, control, NC, and shTUG1 groups are shown (n = 8 per group). c Quantification of the total flux, compared with the LV-NC group: ***P < 0.001. d HE staining of lungs from the normal saline, control, NC, and shTUG1 groups after injection of physiological saline or CRC cells transfected with NC-siRNA or TUG1 shRNA. e Quantification of lung metastatic foci, compared with the LV-NC group: ***P < 0.001.

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