Fig. 3: Combined low expression of Bax, Bak and Smac is a combinatorial marker candidate for improved progression-free survival. | Cell Death & Disease

Fig. 3: Combined low expression of Bax, Bak and Smac is a combinatorial marker candidate for improved progression-free survival.

From: Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma

Fig. 3

a Expression profiles based on the H scores of Bax, Bak and Smac (blue: automated H score below median, red: above median) in n = 50 patients. b Survival analysis for the cohort based on the expression profiles shown in a. Log-rank test for trend was used to compare three Kaplan–Meier curves representing patients with low Bax, Bak and Smac H scores (blue) vs. mixed and high expression (black and red, respectively).

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