Fig. 6: CZ promotes immunosuppressive ability of MSCs in rat model. | Cell Death & Disease

Fig. 6: CZ promotes immunosuppressive ability of MSCs in rat model.

From: Chlorzoxazone, a small molecule drug, augments immunosuppressive capacity of mesenchymal stem cells via modulation of FOXO3 phosphorylation

Fig. 6

a Schematic diagram of acute kidney injury rat model. b PAS staining of pathological section of kidney tissue of normal rat and rat model administered by DMSO or CZ-treated MSCs, respectively. Arrows indicate fibrinoid necrosis (long arrows) and mesangial cell proliferation (short arrows) of glomeruli, respectively. c Individual maps of urine protein, urine creatinine, and serum creatinine in acute kidney injury rat model administered by DMSO or CZ-treated MSCs, respectively. n = 6, **P < 0.01, ***P < 0.001, scale bars: 200 μm.

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