Fig. 7: Schematic diagram of CZ-mediated FOXO3 signaling.

CZ inhibits FOXO3 phosphorylation thus prevent FOXO3 from translocating to cytoplasm, retaining FOXO3 inside nucleus to transcript downstream genes.
CZ inhibits FOXO3 phosphorylation thus prevent FOXO3 from translocating to cytoplasm, retaining FOXO3 inside nucleus to transcript downstream genes.