Fig. 7: GGA reduced pro-apoptotic markers, and improved cell survival.
From: Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity
a Gentamicin exposure increased apoptosis markers including cleaved PARP (clvPARP) and CHOP, and also decreased Bcl-xL content. b GGA significantly reduced cleaved PARP during gentamicin exposure. c Gentamicin increased the fraction of dead cells, and decreased total cell number as measured by propidium iodide and Hoechst staining, respectively (Genta vs. Control panels); bars = 50 µm. d Gentamicin significantly reduced cell viability, whereas GGA significantly improved survival; *P < 0.05; n = 6.
