Fig. 1: FADS1 is upregulated in LSCC tissues and predicts poor survival.

a Box plots showed mRNA levels of FADS1 in HNSC tissues and noncancerous tissues in TCGA datasets from GEPIA. b Box plots showed that expression levels of FADS1 were gradually increased with T stage progression. c QRT-PCR analysis of FADS1 mRNA in 30 paired LSCC tumor tissues. *P < 0.05, two-tail paired t-test. d Immunohistochemistry staining of FADS1 in LSCC tissues, laryngeal severe dysplasia tissues and normal laryngeal tissues under ×100 and ×400 magnification respectively. e Kaplan–Meier overall survival analysis stratified by FADS1 expression in patients with LSCC. f Kaplan–Meier overall survival analysis stratified by FADS1 expression in patients with LSCC recurrence and chemotherapy.