Fig. 7: The effects of CXCL11 on PC cells proliferation and migration. | Cell Death & Disease

Fig. 7: The effects of CXCL11 on PC cells proliferation and migration.

From: The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer

Fig. 7

a Relative expression of CXCL11 by qRT-PCR and western blotting in PC cell lines. b, c Relative expression of CXCL11 by qRT-PCR and western blotting in PC cells with CXCL11-overexpression vector and siRNA. d, e The CCK-8 assays were performed to analyze the effects of CXCL11 on cell proliferation. f–i EdU assays were performed to analyze the effects of CXCL11 on cell proliferation. Magnification, ×100; scale bar, 100 μm. j The flow cytometry analysis of the effect of CXCL11 expression alteration on cell apoptosis. k, l Wound-healing assays measured the effect CXCL11 on PC cell migration ability. m Transwell assays measured the effect CXCL11 on PC cell migration ability. n EMT-related protein was analyzed by western blotting assays in transfected PC cells. The data are presented as mean ± SD from three independent experiments. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001.

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