Fig. 1: Some common clinical patterns of CRC metastasis formation.
From: Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer

Pluri-metastatic disease with a wide diffusion to liver or b to multiple organs (most frequently including liver, lungs, lymphnodes), and oligometastatic disease with “low burden” single organ involvement (liver in c, lungs in d). The disease pattern here studied is depicted in e.