Fig. 3: Primary and metastatic tumor genes comparison.
From: Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer
Venn Diagrams, tumor mutation burden (TMB), microsatellite instability (MSI) status (left panel) and descriptive pairwise comparison heatmap of all coding genetic variants of strong or potential/unknown clinical significance (right panel) for each patient (a SV, b CL, c FA, d LN). Cyan indicates shared genetic variations, yellow PT private variations, red MT private variations. Coding variations in MSI-associated genes of potential clinical significance are indicated, if present, with a red arrow. “Variant calling” and “TMB calculation” were based on not related algorithms, thus the real number of coding variants cannot be derived from TMB and vice versa (see Manufacturer Instructions at https://emea.support.illumina.com/).
