Table 1 Clinicopathological characteristics and genetic concordance in the enrolled patients.

From: Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer

Patient Initials

PT localization

Pathologic stage at diagnosis

Max diameter of PT at gross dissection (cm)

Adjuvant chemotherapy

IS in PT

Time-to-lung metastasis (months)

Max diameter of nodule at CT scan (cm)

TMB in PT (mut/Mb)

TMB in MT (mut/Mb)

No. of shared mutations

Genetic sharing PT/MT

Number of new coding genetic variants in MT

SV

Sigmoid colon

pT2pN0pV1pR0G2

4.0

No

Low

15

1.2

1.9

1.6

141

81.9%

31

CL

Left colon

pT4bpN0pV0pR0G2

3.5

Four cycles (CAPOX)

Int

52

1.3

7.0

694.3

25

12.2%

40

FA

Left colon

pT3pN0pV0pR0G2

3.0

Two cycles (CAPOX)

Int

53

2.0

21.0

6.3

24

13.3%

149

LN

Rectum

pT1pNpV0pR0G2

2.5

No

NE

70

1.1

8.8

8.6

165

95.9%

3

  1. CAPOX capecitabine and oxaliplatin, CT computed tomography, Int intermediate, IS ImmunoScore, MT metastatic tumor, NE not evaluable, PT primary tumor; TMB tumor mutation burden.