Table 1 Clinicopathological characteristics and genetic concordance in the enrolled patients.
From: Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer
Patient Initials | PT localization | Pathologic stage at diagnosis | Max diameter of PT at gross dissection (cm) | Adjuvant chemotherapy | IS in PT | Time-to-lung metastasis (months) | Max diameter of nodule at CT scan (cm) | TMB in PT (mut/Mb) | TMB in MT (mut/Mb) | No. of shared mutations | Genetic sharing PT/MT | Number of new coding genetic variants in MT |
---|---|---|---|---|---|---|---|---|---|---|---|---|
SV | Sigmoid colon | pT2pN0pV1pR0G2 | 4.0 | No | Low | 15 | 1.2 | 1.9 | 1.6 | 141 | 81.9% | 31 |
CL | Left colon | pT4bpN0pV0pR0G2 | 3.5 | Four cycles (CAPOX) | Int | 52 | 1.3 | 7.0 | 694.3 | 25 | 12.2% | 40 |
FA | Left colon | pT3pN0pV0pR0G2 | 3.0 | Two cycles (CAPOX) | Int | 53 | 2.0 | 21.0 | 6.3 | 24 | 13.3% | 149 |
LN | Rectum | pT1pNpV0pR0G2 | 2.5 | No | NE | 70 | 1.1 | 8.8 | 8.6 | 165 | 95.9% | 3 |