Table 2 Summary of patient by patient CRC key driver mutated genes (strong or potential clinical significance according to four-tiered structure of AMP/ACMG consensus).
From: Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer
Patient | PT mutated genes | MT mutated genes |
|---|---|---|
SV | APC, ERBB2, TP53 | APC, ERBB2, TP53 |
CL | APC, ERBB2, KRAS, PI3KCA, SMAD4, TP53 | ERBB2, TP53 |
FA | RASA1, TP53. | APC, BRAF, ERBB2, TP53 |
LN | APC, ERBB2, KRAS (two pathogenic mutations KRASp.Gly12Val and KRASp.Cly13Asp), TP53 | APC, ERBB2, KRAS (p.Gly12Val), TP53 |
