Fig. 6: ZNF750 is negative correlated with FOXC2 in squamous cell carcinoma. | Cell Death & Disease

Fig. 6: ZNF750 is negative correlated with FOXC2 in squamous cell carcinoma.

From: Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma

Fig. 6

a The log2 ratio heatmap of differences expression of ZNF750 and FOXC2 between ESCC tissues and paired normal tissues. Red represents up-regulation and blue represents down-regulation. b Correlation of differences expression between ZNF750 mRNA and FOXC2 mRNA. The horizontal axis is the log2 ratio of FOXC2 and the vertical axis is the log2 ratio of ZNF750. Red dot showed the same differences expression trend between ZNF750 and FOXC2 mRNA. Blue dot showed the opposite trend between them. c–e Correlation analysis between ZNF750 mRNA and FOXC2 in 92 ESCC samples, 513 HNSC samples, 494 LUSC and 300 CESC samples from TCGA. The horizontal axis is the expression of ZNF750 mRNA and the vertical axis is the mRNA expression of FOXC2. f Diagram showing how loss-function of ZNF750 contributes to tumorigenesis of ESCC via DANCR/miR-4707-3p/FOXC2 axis that works in a ceRNA manner.

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